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PPI Drugs & Kidney Damage

What is a Proton Pump Inhibitor?

Proton Pump Inhibitor (PPI), is a type of medication used to treat a myriad of gastrointestinal issues including heartburn, acid reflux, stomach ulcers and inflammation of the esophagus.

Kidney Damage and the Use of PPI Medications

The use of the PPI medications Prilosec, Prevacid and Nexium has been linked to kidney damage in some users. If you suffered from any type of kidney damage including acute kidney injury, chronic kidney disease and interstitial nephritis you could be eligible for compensation.

FDA Warning

In 2014, The Food and Drug Administration (FDA) mandated a new warning for PPI medications including Prilosec, regarding the link between these drugs and interstitial nephritis: ​

"Acute interstitial nephritis has been observed in patients taking PPIs including Prilosec. Acute interstitial nephritis may occur at any point during PPI therapy and is generally attributed to idiopathic hypersensitivity reaction. Discontinue Prilosec if acute interstitial nephritis develops."

What is Interstitial Nephritis?

Interstitial Nephritis is a kidney disorder that causes inflammation between the kidney tubules. Once this inflammation occurs, it can cause many symptoms that range from mild to severe. Interstitial Nephritis can be acute (sudden occurrence) or chronic. This serious condition can lead to severe complications including kidney failure if left untreated.

Symptoms Include:

  • A decrease in urination
  • Appearance of blood in the urine
  • Water retention/bloating/weight increase
  • Fever
  • Fatigue
  • Confusion
  • Nausea
  • Vomiting
  • Diarrhea
  • Rash
  • Inflammation
  • High blood pressure

If you or someone you love is exhibiting any of these symptoms, please contact a health professional to determine if you may have kidney disease.

Kidney problems?

If you used Prilosec, Nexium or Pervacid and developed chronic or acute kidney conditions, please contact 1-800-LAW-FIRM for a free and confidential consultation. You may be eligible to receive compensation.


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